ISSN 2564-7784 | E-ISSN 2564-7040
Original Article
There is a Significant Relationship between Renal Resistive Index and Increased Renal Cortical Stiffness in Patients with Preserved Renal Function
1 Department of Radiology, Health Sciences University, Adana Health Practice and Research Center, Adana, Turkey  
2 Department of Internal Medicine, Health Sciences University, Adana Health Practice and Research Center, Adana, Turkey  
Eur J Ther ; : -
DOI: 10.5152/EurJTher.2018.817
Key Words: Conventional ultrasonography, cortical stiffness, renal resistive index


Objective: We aimed to investigate the relationship between cortical stiffness (CS) determined by shear wave elastography (SWE) and conventional ultrasonography (USG) parameters and to identify the determining parameters that increased CS.


Methods: 229 patients who underwent renal USG were included in our study. In addition to conventional renal USG, SWE was performed. Patients were divided into two groups with and without increased CS.


Results: The median CS value of the patients included in the study was 4.92 kPa. The increased CS value was taken as the limit value of 5.0 kPa. The age, creatinine and eGFR levels and presence of diabetes and hypertension were significantly higher in increased CS group (p<0.05). It was found that cortical echogenicity increase (stage I-II), renal resistance index (RRI) and acceleration time values were significantly higher in patients with increased CS (p<0.05). When logistic regression analysis was performed to identify patients with increased CS, we found that RRI, diabetes presence, cortical echogenicity stage I-II independently predicted an increase in CS (p<0.05). According to this analysis, RRI (every-0.1), diabetes, cortical echogenicity stage I and stage II increased the risk of increased CS by 2.3 times, 14%, 10.5% and 18.2% respectively. In ROC analysis for RRI, the area under the curve was 0.719, and when the cut-off value for RRI was taken as 0.70, it was found to be 71.1% sensitive and 64.3% specific for increased CS.


Conclusion: The increase in renal echogenicity and RRI obtained by conventional USG studies were independently identifies patients with increased CS.

Key Words
AVES | Copyright © 2018 European Journal of Therapeutics | Latest Update: 09.10.2018