ISSN 2564-7784 | E-ISSN 2564-7040
Review
Use of Botulinum Toxin in Urology: A Review of the Literature
1 Department of Urology, Gaziantep University School of Medicine, Gaziantep, Turkey  
2 Department of Urology, Marmara University School of Medicine, İsatnbul, Turkey  
3 Department of Urology, Vanderbilt University Medical Center, Nashville, USA  
Gaziantep Med J ; : -
DOI: 10.5152/EurJTher.2017.163
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Key Words: Botulinum toxin, neurogenic detrusor overactivity, overactive bladder, detrusor sphincter dyssynergia, benign prostatic enlargement, interstitial cystitis
Abstract

Botulinum toxin (BoNT) is currently preferred as a minimally invasive treatment in the treatment of lower urinary tract pathologies. Although BoNT injections have become widespread throughout the world for the past 5 years, today BoNT Type A (BoNT-A)'s urological use are only licensed in the treatment of neurogenic detrusor overactivity and overactive bladder. Despite the relatively evidence for the use of BoNT-A in benign prostatic enlargement, there is no high level of evidence data for the use of BoNT-A in detrusor sphincter dyssynergia, interstitial cystitis / bladder pain syndrome, and chronic pelvic pain. In this comprehensive review, we aimed to mention the mechanism of action of BoNT, the efficacy of BoNT in various urological disorders, to present the its reliability, and to evaluate the literature data supporting its use.

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AVES | Copyright © 2017 European Journal of Therapeutics | Latest Update: 04.10.2017